Title:
ANTI-VIRAL COMPOUNDS TO TREAT HCV INFECTION
Document Type and Number:
Japanese Patent JP2017171680
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compounds effective in inhibiting replication of Hepatitis C virus.SOLUTION: The present invention provides a compound represented by formula I or a pharmaceutically acceptable salt (D is substituted/unsubstituted 3-6 membered heterocycle; L3 is H/halogen-substituted benzene ring; X is pyrrolidine ring; L1 and L2 are halogen-substituted/unsubstituted benzimidazole ring; A and B are pyrrolidine ring; Y and Z are -C(O)-R-NH-C(O)-O-R; Ris substituted/unsubstituted C1-C6 alkylene; Ris a methyl group).SELECTED DRAWING: None
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Inventors:
DEGOEY DAVID A
KATI WARREN M
CHARLES W HUTCHINS
DONNER PAMELA L
ALLAN C KRUEGER
RANDOLPH JOHN T
MOTTER CHRISTOPHER E
NELSON LISSA T
SACHIN V PATEL
MATULENKO MARK A
KEDDY RYAN G
TAMMIE K JINKERSON
HUTCHINSON DOUGLAS K
FLENTGE CHARLES A
WAGNER ROLF
MARING CLARENCE J
TUFANO MICHAEL D
BETEBENNER DAVID A
ROCKWAY TODD W
LIU DACHUN
PRATT JOHN K
SARRIS KATHY
KEVIN R WOLLER
WAGAW SABLE H
JEAN C CALIFANO
LI WENKE
DANIEL D CASPI
BELLIZZI MARY E
GAO YI
KATI WARREN M
CHARLES W HUTCHINS
DONNER PAMELA L
ALLAN C KRUEGER
RANDOLPH JOHN T
MOTTER CHRISTOPHER E
NELSON LISSA T
SACHIN V PATEL
MATULENKO MARK A
KEDDY RYAN G
TAMMIE K JINKERSON
HUTCHINSON DOUGLAS K
FLENTGE CHARLES A
WAGNER ROLF
MARING CLARENCE J
TUFANO MICHAEL D
BETEBENNER DAVID A
ROCKWAY TODD W
LIU DACHUN
PRATT JOHN K
SARRIS KATHY
KEVIN R WOLLER
WAGAW SABLE H
JEAN C CALIFANO
LI WENKE
DANIEL D CASPI
BELLIZZI MARY E
GAO YI
Application Number:
JP2017114480A
Publication Date:
September 28, 2017
Filing Date:
June 09, 2017
Export Citation:
Assignee:
ABBVIE IRELAND UNLIMITED CO
International Classes:
C07D401/14; A61K31/4184; A61K31/428; A61K31/444; A61K31/4545; A61K31/506; A61K31/5377; A61K31/55; A61P31/14; C07D403/14; C07D405/14; C07D413/14; C07D417/14
Domestic Patent References:
| JP6159830B2 | 2017-07-05 | |||
| JP5911838B2 | 2016-04-27 | |||
| JPH09255949A | 1997-09-30 | |||
| JPS62195307A | 1987-08-28 |
Foreign References:
| WO2010017401A1 | 2010-02-11 | |||
| US3225061A | 1965-12-21 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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