Title:
ANTIALLERGIC COMPOSITION
Document Type and Number:
Japanese Patent JPH04244028
Kind Code:
A
Abstract:
PURPOSE: To obtain an antiallergic composition for providing protection against allergic reaction and to provide a method for utilizing the composition for treatment of the allergic reaction. CONSTITUTION: This allergic composition capable of providing a synergistic protection against allergic reaction such as antigen-induced type death in an animal includes a combination of PAF antagonist and LTD4 antagonist, and the composition is utilized for a treatment of the allergic reaction. The PAF antagonist is 5- 3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3- a][1,4]diazepin-2-yl]-2-propynyl}phenanthridin-6(5H)-one, etc., and the LTD4 antagonist is (E)-4-[3-[2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenylamino]-2,2- diethyl-4-oxobutanoic acid, etc.
Inventors:
MAAGARETSUTO ODONERU
AN UERUTON
AN UERUTON
Application Number:
JP21600991A
Publication Date:
September 01, 1992
Filing Date:
August 01, 1991
Export Citation:
Assignee:
HOFFMANN LA ROCHE
International Classes:
A61K31/34; A61K31/35; A61K31/40; A61K31/41; A61K31/425; A61K31/44; A61K31/445; A61K31/47; A61K31/505; A61K31/55; A61P37/08; A61K31/19; A61P43/00; (IPC1-7): A61K31/19; A61K31/34; A61K31/35; A61K31/40; A61K31/41; A61K31/425; A61K31/44; A61K31/445; A61K31/47; A61K31/505; A61K31/55
Attorney, Agent or Firm:
Heikichi Odashima
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