Title:
抗菌性ビグアニド金属錯体
Document Type and Number:
Japanese Patent JP6424111
Kind Code:
B2
Abstract:
A compound comprising a metal species and a biologically acceptable ligand, wherein the biologically acceptable ligand comprises a biguanide moiety, and wherein the biologically acceptable ligand forms a complex with the metal species in which the metal species is stabilised in an oxidation state greater than 1+. Compositions and medical devices comprising the compound. A method for the treatment or prophylaxis of microbial, including bacterial, infections, comprising the use of such compounds, compositions or medical devices.
Inventors:
Brian Greener
Application Number:
JP2015031988A
Publication Date:
November 14, 2018
Filing Date:
February 20, 2015
Export Citation:
Assignee:
SMITH & NEPHEW PUBLIC LIMITED COMPANY
International Classes:
C07F1/10; A61K31/155; A61L31/00; A61P31/04; C07C281/16
Domestic Patent References:
| JP32106A | ||||
| JP2001508041A | ||||
| JP9510629A | ||||
| JP2002524475A | ||||
| JP217071A | ||||
| JP9208411A | ||||
| JP2004510794A | ||||
| JP2003517463A | ||||
| JP6511188A |
Foreign References:
| US3468898 | ||||
| US5223149 | ||||
| US3702298 |
Other References:
Chemical Reviews,1961,Vol.61,pp.313-359
Biochemical Pharmacology,2003,Vol.66,pp.663-677
Journal of Inorganic Biochemistry,1999,Vol.76,pp.251-257
Inorganica Chimica Acta,1990,Vol.174,pp.257-262
Journal of the Indian Chemical Society,1970,Vol.47,No.10,pp.1021-1022
Journal of Inorganic and Nuclear Chemistry,1976,Vol.38,pp.1635-1640
Journal of Electron Spectroscopy and Related Phenomena,1974,Vol.4,pp.351-354
Inorganic Syntheses,1960,Vol.6,pp.71-74
Journal of the Indian Chemical Society,1976,Vol.53,pp.719-721
Journal of the Chemical Society A: Inorganic,Physical,Theoretical,1969,pp.1304-1305
Anales de quimica,Serie B,Quimica inorganica y quimica analitica,1982,Vol.78,pp.83-86
Vijnana Parishad Anusandhan Patrika,1978,Vol.21,No.3,pp.253-256
Afinidad,1980,Vol.37,pp.137-140
European Journal of Inorganic Chemistry,2003,pp.4308-4312
Biochemical Pharmacology,2003,Vol.66,pp.663-677
Journal of Inorganic Biochemistry,1999,Vol.76,pp.251-257
Inorganica Chimica Acta,1990,Vol.174,pp.257-262
Journal of the Indian Chemical Society,1970,Vol.47,No.10,pp.1021-1022
Journal of Inorganic and Nuclear Chemistry,1976,Vol.38,pp.1635-1640
Journal of Electron Spectroscopy and Related Phenomena,1974,Vol.4,pp.351-354
Inorganic Syntheses,1960,Vol.6,pp.71-74
Journal of the Indian Chemical Society,1976,Vol.53,pp.719-721
Journal of the Chemical Society A: Inorganic,Physical,Theoretical,1969,pp.1304-1305
Anales de quimica,Serie B,Quimica inorganica y quimica analitica,1982,Vol.78,pp.83-86
Vijnana Parishad Anusandhan Patrika,1978,Vol.21,No.3,pp.253-256
Afinidad,1980,Vol.37,pp.137-140
European Journal of Inorganic Chemistry,2003,pp.4308-4312
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe