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Title:
安定性を増強させた抗菌溶液
Document Type and Number:
Japanese Patent JP6820921
Kind Code:
B2
Abstract:
Provided are antimicrobial solutions, including catheter lock solutions. In some embodiments, the solution contains an antibiotic (e.g., minocycline or trimethoprim), EDTA, and an alcohol (e.g., ethanol), wherein the pH of the solution is adjusted to about 6-8 to reduce precipitation. Methods of using the solutions and kits are also provided.

Inventors:
Rosenblatt Joel
Lard Issam
Application Number:
JP2018522975A
Publication Date:
January 27, 2021
Filing Date:
November 04, 2016
Export Citation:
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Assignee:
BOARD OF REGENTS,THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
A61K31/505; A61J15/00; A61K9/08; A61K31/65; A61K47/02; A61K47/04; A61K47/10; A61K47/18; A61L31/16; A61M1/00; A61M25/00; A61P31/04
Domestic Patent References:
JP2006526664A
Foreign References:
US7601731
Other References:
Journal of Medical Microbiology,2009年,58,pp.936-944
Antimicrobial Agents and Chemotherapy,2007年,51(1),pp.78-83
Antimicrobial Agents and Chemotherapy,2013年,57(1),pp.586-588
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto