NEW MATERIAL:The antibiotic substance KA-6643-G of formula, its salt or its ester.
USE: Antibiotic substance.
PROCESS: A bacterial strain belonging to Streptomyces genus and capable of producing antibiotic substance KA-6643-G (e.g. streptomyces KC-6643-M-162-175 strain; FERM-R No.5890), is cultured under aerobic conditions at 3W35°C, preferably 27W33°C, especially by submerged technique, and the antibiotic substance KA-6643-G of formula can be separated from the cultivation liquid. The compound is stable in the living body and has the folowing physical properties: appearance, white powder; molecular weight (demetermined by mass spectrometry of methyl ester), measured value 342.1224, calculated value 342.1246 (as C15H22N2O5S); molecular formula, C14H19N2O5O.Na; solubility, soluble in water and methanol, insoluble in acetone, ethyl acetate, and chloroform; etc.
NAKAYAMA MASATO
IWASAKI AKIO
KIMURA SHIGERU
MIZOGUCHI TOSHIMI
TANABE SOUHEI
MURAKAMI AKIRA
ITOU HISAKATSU
MORI TOSHITO
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