Title:
ガストリン放出ペプチド前駆体に対する抗体及びその使用
Document Type and Number:
Japanese Patent JP5391071
Kind Code:
B2
Abstract:
Disclosed is a novel high-sensitive ProGRP measurement method, which is free from problems such as the fluctuations in measurement values and the operational constraints (e.g., the constraints on the handling of a sample). Specifically disclosed is a method for the measurement of a gastrin-releasing peptide precursor and/or a digested product thereof using at least two different antibodies each of which can recognize an epitope represented by the amino acid sequence consisting of amino acid 47 to amino acid 68 of the amino acid sequence set forth in SEQ ID NO:1. The method can detect a ProGRP or a digested product thereof in a refrigerated sample within a shorter period, by using the sample in a smaller amount, and with a higher degree of detective sensitivity, compared with the conventional methods.
Inventors:
Katsumi Aoyagi
Izawa Yukiji
Izawa Yukiji
Application Number:
JP2009537894A
Publication Date:
January 15, 2014
Filing Date:
September 29, 2008
Export Citation:
Assignee:
Advanced Life Science Institute Co., Ltd.
International Classes:
C07K16/18; C12N5/10; C12N15/09; G01N33/53; G01N33/574; C12P21/08
Foreign References:
| WO2006117994A1 | 2006-11-09 |
Other References:
JPN6013009172; カタログ ＣａｎＡｇ ＰｒｏＧＲＰ ＥＩＡ， Ｐｒｏｄ． Ｎｏ．２２０-８５， Ｆｕｊｉｒｅｂｉｏ Ｄｉａｇｎｏｓｔｉｃｓ ＡＢ， Ｓｅｐｔ．２００７
JPN6013009173; Ｅｎｄｏｃｒｉｎｏｌｏｇｙ，Ｖｏｌ．１４８，Ｎｏ．３（Ｍａｒ．２００７）ｐ．１３３０-１３３９
JPN6013009173; Ｅｎｄｏｃｒｉｎｏｌｏｇｙ，Ｖｏｌ．１４８，Ｎｏ．３（Ｍａｒ．２００７）ｐ．１３３０-１３３９
Attorney, Agent or Firm:
Norio Saeki
Nakamura Tadashi Exhibition
Nakamura Tadashi Exhibition
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