ANTIBODY AND ANTIBODY-CONTAINING COMPOSITION

Japanese Patent JP2016034975

A

PROBLEM TO BE SOLVED: To provide antibodies using bacterial cells as antigens, and to provide an antibody-containing composition comprising the antibody and a base.SOLUTION: For many of diseases mediated by bacteria or the like, the proliferation of bacteria is one of the causes of the diseases, and sometimes substances released by bacteria become the causes of the diseases. In the latter case, when the diseases are to be treated with antibodies, it is required to produce the antibodies using causative substances for the diseases as antigens. However, it is difficult to search for essential causative substances from among substances released by the bacteria. Then, an avian species is immunized with a disruption solution produced by disrupting bacterial cells as an antigen to produce a (polyclonal) antibody that can bind to an antigen as well as a substance secreted by the antigen and capable of accelerating the worsening of a symptom. An antibody produced using a surface protein of a virus as an antigen is expected to inhibit the infection with the virus.SELECTED DRAWING: None

TSUKAMOTO YASUHIRO

JP2015227426A

March 17, 2016

November 20, 2015

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OSTRICH PHARMA KK
IMMORTAL SPIRIT LTD

C07K16/12; A61K39/395; C07K16/08; C07K16/10

JP2005537028A	2005-12-08
JP2010013361A	2010-01-21
JP2009023985A	2009-02-05
JP2007084495A	2007-04-05

VACCINE, vol. 24, JPN6017024433, 2006, pages 5571 - 5583, ISSN: 0003796626
ウイルス, vol. 58, no. 2, JPN6017024434, 2008, pages 155 - 164, ISSN: 0003796627

Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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