Title:
抗原提示系およびT-細胞の活性化方法
Document Type and Number:
Japanese Patent JP3926842
Kind Code:
B2
Abstract:
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
Inventors:
Kai, Touring
Splend, Jionathan
Brand Mark, Anders
Michael Jackson
Peterson, Par A
Lieuxample, Alain M. de Peautsille de
Lutejurk, Deidee Jiyan
Moriarty, Anne M
Splend, Jionathan
Brand Mark, Anders
Michael Jackson
Peterson, Par A
Lieuxample, Alain M. de Peautsille de
Lutejurk, Deidee Jiyan
Moriarty, Anne M
Application Number:
JP52707696A
Publication Date:
June 06, 2007
Filing Date:
March 08, 1996
Export Citation:
Assignee:
The Scripts Research Institution
International Classes:
C12N15/09; A61K35/14; A61K48/00; A61P35/00; C07K14/025; C07K14/145; C07K14/705; C07K14/74; C12N5/07; C12N5/0783; C12N5/10; C12N15/12; C12N15/85; C12P21/02; A61K38/00; A61K39/00; A61P37/04
Foreign References:
| WO1993001557A1 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Takeshi Funayama
Naoya Fushimi
Takeshi Funayama
Naoya Fushimi