Title:
神経保護及び神経再生用の抗原提示細胞
Document Type and Number:
Japanese Patent JP2006503808
Kind Code:
A
Abstract:
Pharmaceutical compositions and methods for preventing or inhibiting neuronal degeneration, or for promoting nerve regeneration, in the central nervous system (CNS) or peripheral nervous system (PNS), in the treatment of an injury, disorder or disease of the CNS or PNS, comprise antigen-presenting cells, preferably dendritic cells, that have been pulsed with an agent selected from the group consisting of: (a) a nervous system (NS)-specific antigen or an analog thereof; (b) a peptide derived from an NS-specific antigen or from an analog thereof, or an analog or derivative of said peptide; (c) a copolymer selected from the group consisting of Copolymer 1, a Copolymer 1-related peptide or polypeptide, and poly-Glu<50> Tyr<50>; and (d) a non-self antigen.
Inventors:
Eisenbach-Schwartz, Mikal
Cohen, Abraham
Cohen, Abraham
Application Number:
JP2004512658A
Publication Date:
February 02, 2006
Filing Date:
June 12, 2003
Export Citation:
Assignee:
YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED
International Classes:
A61K35/26; A61K35/14; A61K35/28; A61K35/36; A61K39/00; A61P3/02; A61P7/04; A61P9/10; A61P17/02; A61P21/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/36; A61P27/02; A61P27/06; A61P43/00; C12N5/07; C12N5/0784; C12N5/0793; C07K14/705
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda