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Title:
ANTIINFLAMMATORY 17-SPIROANDROSTENES
Document Type and Number:
Japanese Patent JPS58216200
Kind Code:
A
Abstract:
Topical antiinflammatory activity is exhibited by steroids having the formulaand the 1,2-dehydro and 15,16-dehydro derivatives thereof, whereinR1 is hydrogen, alkyl, carboxyl, oralkoxycarbonyl;R2 is hydrogen, chlorine, bromine, fluorine, methyl, hydroxyl or a conventional hydrolyzable ester thereof, methoxy, or oxo (=O);R3 is carbonyl or β-hydroxymethylene;R4 is hydrogen or fluorine;R5 is hydrogen, methyl of fluorine;X and Y are the same or different, and each is S, O, NH, N-CH3, SO or S02; andnis1,2,3,4or5.

Inventors:
RABI KEE BAAMA
Application Number:
JP9219683A
Publication Date:
December 15, 1983
Filing Date:
May 24, 1983
Export Citation:
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Assignee:
SQUIBB & SONS INC
International Classes:
A61K31/58; A61P29/00; C07J1/00; C07J21/00; C07J33/00; C07J43/00; (IPC1-7): A61K31/58; C07J21/00; C07J33/00
Foreign References:
US3274182A1966-09-20
US3476746A1969-11-04
Attorney, Agent or Firm:
Aoyama Aoi



 
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