To provide an antimicrobial composition comprising silver nanoparticles that are scalable to high volume manufacturing and utilize chemicals that are relatively non-hazardous.
The composition is for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The method includes treating a device with the silver nanoparticle compositions, including devices as woven wound care materials, catheters, patient care devices, and collagen matrices.
GIBBINS BRUCE L
CORNELL KEN A
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Masakazu Ito
Yuko Hara