抗悪性腫瘍剤およびその製造方法と用途

Japanese Patent JP5718450

B2

The present invention relates to substance 3787-5-1 represented by formula (I) and pharmaceutically permissible salts thereof. Substance 3787-5-1 is useful for the prevention and treatment of a disease caused by a cell proliferative disorder, particularly a malignant tumor, because it has antineoplastic activity acting alone and also enhances the antineoplastic activity of other antineoplastic agents. This substance can be produced by culturing a microorganism of the genus Phytohabitans that is capable of producing substance 3787-5-1, particularly Phytohabitans sp. 3787-5, and collecting substance 3787-5-1 from the culture product thereof.

JP3468211	(+)-ESTRONE DERIVATIVE
JPH0635476	INDUSTRIAL APPLICABILITY: Estrane-and-androstane derivatives, a method for producing the same, and a diagnostic agent containing the same.
WO/2000/053619	14.BETA., 17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS

Hiroshi Donada
Daisuke Matsuda
Ryuji Uchida
Yoko Takahashi
Satoshi Omura

JP2013502361A

May 13, 2015

February 28, 2012

Click for automatic bibliography generation  

Kitasato Institute

C07J53/00; A61K31/56; A61K38/00; A61K45/00; A61P35/00; A61P43/00; C12P15/00

JPN6014039490; Ｊｏｕｒｎａｌ　ｏｆ　Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔｓ ７１（２）, 2008, ２６９-２７１
JPN6014039491; Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　Ｒｅｓｅａｒｃｈ　Ｃｏｍｍｕｎｉｃａｔｉｏｎｓ ２０，　Ｓｕｐｐｌｅｍｅｎｔ　Ｖ, 1988, ２３-２６
JPN6014039492; Ｊｏｕｒｎａｌ　ｏｆ　Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔｓ ６８（７）, 2005, １０２２-１０３０
JPN6014039493; Ｉｎｔｅｒｎａｔｉｏｎａｌ　Ｊｏｕｒｎａｌ　ｏｆ　Ｓｙｓｔｅｍａｔｉｃ　ａｎｄ　Ｅｖｏｌｕｔｉｏｎａｒｙ　Ｍｉｃｒｏｂｉｏｌｏｇｙ ６０, 2010, ２６５２-２６５８
JPN6014039490; Ｊｏｕｒｎａｌ　ｏｆ　Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔｓ ７１（２）, 2008, ２６９-２７１
JPN6014039491; Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　Ｒｅｓｅａｒｃｈ　Ｃｏｍｍｕｎｉｃａｔｉｏｎｓ ２０，　Ｓｕｐｐｌｅｍｅｎｔ　Ｖ, 1988, ２３-２６
JPN6014039492; Ｊｏｕｒｎａｌ　ｏｆ　Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔｓ ６８（７）, 2005, １０２２-１０３０
JPN6014039493; Ｉｎｔｅｒｎａｔｉｏｎａｌ　Ｊｏｕｒｎａｌ　ｏｆ　Ｓｙｓｔｅｍａｔｉｃ　ａｎｄ　Ｅｖｏｌｕｔｉｏｎａｒｙ　Ｍｉｃｒｏｂｉｏｌｏｇｙ ６０, 2010, ２６５２-２６５８

Yusuke Hiraki
Satoshi Fujita
Natsuo Tanaka
Hidetoshi Hanai

Previous Patent: 金属ナノワイヤを有する透明導体のエッチングパターン形成

Next Patent: AIR CLEANER