Title:
治療剤としての抗酸化ニトロキシドおよびニトロン
Document Type and Number:
Japanese Patent JP2004527520
Kind Code:
A
Abstract:
The invention provides novel adamantane compounds having one of the following formulas:wherein:R1 and R3 are H, OH, alkyl, cycloalkyl, amino or aryl, and can be the same or different;R2 is H, NH2, alkyl, OH, COOH, amino, amide, or carbamate;R4-R8 are H, OH, NH2, alkyl, OH, COOH, ester, amino, amide, or alkyloxy, and can be the same or different;R9-R14 are H, alkyl, or phenyl, and can be the same or different;and wherein when any of R1-R8 is amino, the compounds are the free bases and their acid addition salts.The present invention also relates to compositions and methods for treating and/or preventing neurological and inflammatory disorders in a patient by administering a therapeutically effective amount of the compounds of formula (I), (II) or (III) and a pharmaceutically acceptable carrier.
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Inventors:
One, going
Lalique, James W.
Lalique, James W.
Application Number:
JP2002576883A
Publication Date:
September 09, 2004
Filing Date:
April 02, 2002
Export Citation:
Assignee:
Panorama Research, Incorporated
International Classes:
A61K31/00; A61P9/00; A61P9/10; A61P11/06; A61P19/02; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/28; A61P25/30; A61P29/00; A61P39/06; C07C271/24; C07C291/00; A61P1/04; C07C291/02; C07C291/06; (IPC1-7): C07C271/24; A61K31/00; A61P1/04; A61P9/00; A61P9/10; A61P11/06; A61P19/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/28; A61P25/30; A61P29/00; A61P39/06; C07C291/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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