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Title:
ANTIPROTOZOAN COMPOSITION CONTAINING CASPOFUNGIN OR ITS SALT AND BIGUANIDE-BASED COMPOUND OR ITS SALT
Document Type and Number:
Japanese Patent JP2013234176
Kind Code:
A
Abstract:

To provide an antiprotozoan composition useful to keratitis, especially acanthamoeba keratitis which is one of eye infection due to wearing contact lenses.

An antiprotozoan composition includes caspofungin (a kind of macrocyclic lipopeptide echinocandin, also named as 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10R,12S-10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithin]-5-[(3R)-3-hydroxy-L-ornithin]pneumocandin B0) or its salt, and a biguanide-based compound or its salt. As the biguanide-based compound, polyhexanide, chlorhexidine and alexidine are preferably cited.


Inventors:
IBUKI HAJIME
HIKITA KOJI
KIDO KAZUTAKA
Application Number:
JP2013082935A
Publication Date:
November 21, 2013
Filing Date:
April 11, 2013
Export Citation:
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Assignee:
SANTEN PHARMACEUTICAL CO LTD
International Classes:
A61K38/00; A61K31/155; A61K31/785; A61P27/02; A61P33/02; A61P33/04; G02C13/00
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Takaaki Goto