Title:
急性呼吸不全の治療および／または予防の使用のための抗分泌因子
Document Type and Number:
Japanese Patent JP7217760
Kind Code:
B2
Abstract:
The present invention relates to the use of antisecretory factor (AF) protein, homologues, and/or fragments thereof, having equivalent functional activity, and/or a pharmaceutically active salt thereof, for restoring and/or normalizing epithelial barrier function for treating and/or preventing acute respiratory failure. In particular, antisecretory factor (AF) protein, homologues, and/or fragments thereof, having equivalent functional activity, and/or a pharmaceutically active salt thereof, is (are) herein disclosed to be of use in counteracting and/or normalizing fluid transfer across epithelial cell barriers with a significant impact on a large proportion of patients with traumatic lung injury, such as but not limited to patients suffering from abnormal accumulation of fluid in the lung alveoli and/or bronchioles selected from the list of patients suffering from BPD, ARDS, IRDS, sepsis, SIRS, acute pulmonary edema, pneumonia, interstitial pulmonary edema and cardiovascular lung disorder.
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Inventors:
Andesh Larsson
Application Number:
JP2020569003A
Publication Date:
February 03, 2023
Filing Date:
June 26, 2019
Export Citation:
Assignee:
Landmenen Medical Arbe
International Classes:
A61K38/17; A61K35/57; A61K38/10; A61P11/00
Domestic Patent References:
| JP2009535328A | ||||
| JP2009535330A |
Foreign References:
| WO2018015379A1 | ||||
| WO2017009004A1 |
Other References:
Nut. Res. Rev. (2010)vol.23, issue 2, p.300-313
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi