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Title:
ANTITUMOR AGENT
Document Type and Number:
Japanese Patent JPH05238982
Kind Code:
A
Abstract:

PURPOSE: To obtain a new antitumor agent showing higher medicinal effects on cancerous cells, comprising a specific compound as a metabolite of a bacterium belonging to the genus Streptomyces.

CONSTITUTION: An antitumor agent comprising a compound of the formula [R is COCH2CH2CH3 or COCH2CH2CH(CH3)2], namely SF2,418 substance (R= COCH2CH2CH3], piloquinone [R=COCH2CH2CH(CH3)2] or its salt as active ingredient. A daily dose of the compound of the formula is preferably 10-500mg/kg in the case of oral administration and 2-200mg/kg in the case of parenteral administration. In the case of injection, 5-50wt.% of the compound of the formula is contained in injection.


Inventors:
NOSE HIROSHI
HARA OSAMU
YOSHIDA SHIGEMI
FUKUYASU SHUNKAI
NAGASAWA MIEKO
TAKAGI MASAYUKI
Application Number:
JP4380392A
Publication Date:
September 17, 1993
Filing Date:
February 28, 1992
Export Citation:
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Assignee:
MEIJI SEIKA KAISHA
International Classes:
A61K31/12; A61K31/122; A61P35/00; C07C50/34; (IPC1-7): C07C50/34; A61K31/12



 
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