Title:
ANTITUMOR AGENT
Document Type and Number:
Japanese Patent JPH0665075
Kind Code:
A
Abstract:
PURPOSE: To provide an antitumor agent containing 8-formyl-2,5,7-trihydroxy-6- methylflavanone as an active component and a pharmaceutically permissible carrier, having tyrosine kinase inhibiting action and useful for the chemotherapy of cancer.
CONSTITUTION: Desmos chinensis (a tropical plant) is dried, crushed, extracted preferably with hexane or chloroform at room temperature to 50°C and purified to obtain the compound of formula. The objective antitumor agent can be prepared by using the compound of formula as an active component and supporting on a carrier such as synthetic aluminum silicate and microcrystalline cellulose. The daily dose of the compound for adult is 0.1-1g by oral administration.
Inventors:
UMEZAWA KAZUO
KOYANO TAKASHI
HARA TOMOKO
KOYANO TAKASHI
HARA TOMOKO
Application Number:
JP19174092A
Publication Date:
March 08, 1994
Filing Date:
June 25, 1992
Export Citation:
Assignee:
TONEN CORP
UMEZAWA KAZUO
UMEZAWA KAZUO
International Classes:
A61K31/35; A61K31/352; A61K36/18; A61P35/00; C07D311/42; (IPC1-7): A61K31/35; C07D311/42
Attorney, Agent or Firm:
Kohei Kubota (4 outside people)
Next Patent: ANTIMYCOTIC AGENT FOR EXTERNAL USE