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Title:
ANTITUMOR SUBSTANCE 1166D AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPS60100574
Kind Code:
A
Abstract:

NEW MATERIAL:The 1166D substance of formula.

USE: A fungicidal agent having excellent effect to the pathogenic fungi of blossom blight of apple (Valsa ceratosperma).

PREPARATION: A bacterial strain belonging to Streptomyces genus and capable of producing 1166D substance [Streptomyces hygroscopicus D-1166 (FERM-P No.4771)] is cultured under aerobic condition, and the objective 1166D substance of formula is separated from the culture liquid. The compound of formula has the following physicochemical properties. Molecular formula, C38H59O10N; molecular weight, 679.86; [α]d25, +43.4° (C=0.1, in methanol); melting point, 138W 139°C; elemental analysis (as C38H59O10N), C 66.80%, H 8.71%, O 22.98%, N 2.01%; solubility, soluble in methanol, ethanol, acetone, etc., insoluble in n- hexane and water, etc.; appearance, colorless crystal; etc.


Inventors:
OOTAKE NOZOMI
SETO HARUO
SEGAWA TOMOYOSHI
SASAKI TETSUO
SUGITA MASANORI
Application Number:
JP1983000207494
Publication Date:
June 04, 1985
Filing Date:
November 07, 1983
Export Citation:
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Assignee:
NISSHIN FLOUR MILLING CO
TOBISHI PHARMACEUTICAL CO
International Classes:
C07D407/06; A01N43/22; C07D309/00; C07D313/00; C12P17/16; C12R1/465; (IPC1-7): C07D309/00; C07D313/00; C07D407/06; C12P17/16; C12R1/465