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Title:
ANTITUMOR SUBSTANCE BE-60828 AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JP2000026497
Kind Code:
A
Abstract:

To obtain an antitumor substance BE-60828 inhibiting the proliferation of tumor cell, showing an antitumor action, useful for treating cancers as an antitumor agent, etc., by culturing a bacterium belonging to the genus Streptomyces, capable of producing BE60828.

This antitumor substance BE-60828 is shown by the formula, inhibits the proliferation of tumor cell of human and mouse and is useful as a therapeutic agent for cancers in the field of medicine. The antitumor substance BE-60828 is obtained by culturing a bacterium belonging to the genus Streptomyces, capable of producing a compound of formula [e.g. Streptomyces sp. A60828 (Streptomyces sp. A60828 (FERM P-17788), etc.)], and collecting the product from the culture product.


Inventors:
SHIMOKAWA HARUKI
NAKAJIMA SHIGERU
HIRAYAMA MIOKO
KONDO HISAO
OJIRI KATSUHISA
SUDA HIROYUKI
Application Number:
JP20270698A
Publication Date:
January 25, 2000
Filing Date:
July 02, 1998
Export Citation:
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Assignee:
BANYU PHARMA CO LTD
International Classes:
A61K38/00; A61P35/00; C07K7/06; (IPC1-7): C07K7/06; A61K38/00