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Title:
ANTIVIRAL AGENT
Document Type and Number:
Japanese Patent JP2010189434
Kind Code:
A
Abstract:

To provide antiviral agents especially compounds useful for treatment of infection caused by Picornaviridae such as human rhinovirus (HRV), and to provide a method for producing them.

There are provided compounds of formula I, salts thereof, pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising the compounds, and their use in the treatment of picornavirus infections in mammals.


Inventors:
WATSON KEITH
KRIPPNER GUY
STANISLAWSKI PAULINE
MCCONNELL DARRYL
Application Number:
JP2010106686A
Publication Date:
September 02, 2010
Filing Date:
May 06, 2010
Export Citation:
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Assignee:
BIOTA SCIENT MANAGEMENT
International Classes:
C07D261/20; A61K31/416; C07D263/38; A61K31/4184; A61K31/4192; A61K31/423; A61K31/428; A61K31/445; A61K31/454; A61K31/501; A61K31/502; A61K31/517; A61P31/14; A61P31/16; C07D237/26; C07D249/18; C07D263/46; C07D263/58; C07D275/04; C07D277/68; C07D401/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14
Domestic Patent References:
JPH02104584A1990-04-17
JP2003517481A2003-05-27
JP4601901B22010-12-22
JP2000500773A
Foreign References:
WO2000021927A22000-04-20
WO1995004723A11995-02-16
WO2000018761A12000-04-06
WO1998011095A11998-03-19
WO1996004270A11996-02-15
WO1999024440A11999-05-20
Other References:
ZHAO, Z., ET AL.: "Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10(9), JPN6009013568, 2000, pages 963 - 966, ISSN: 0001979990
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Kanamori Koji
Naganuma Akio