Title:
抗ウイルス化合物
Document Type and Number:
Japanese Patent JP2019533007
Kind Code:
A
Abstract:
本発明は、基ＸおよびＲ１〜Ｒ４が、本説明および特許請求の範囲において示されている意味を有する一般式Ｉの新規な化合物、これらの化合物を調製するための方法、およびウイルス感染を処置、予防または改善ためとしてのそれらの使用、ならびにＰＬＡ２Ｇ１６に関連する疾患を処置、予防または改善するためのそれらの使用に関する。【化１】
Inventors:
Fishgang, wolfgang
Whitaker,mark
Yarnold, Christopher John
Pons, Jean-Francois
Kelly, Mark Anthony
Amsegg, Patricia Leonie
Morao, Inaki
Ingram, Peter Neville
Ewa Ivona, Cadek
Whitaker,mark
Yarnold, Christopher John
Pons, Jean-Francois
Kelly, Mark Anthony
Amsegg, Patricia Leonie
Morao, Inaki
Ingram, Peter Neville
Ewa Ivona, Cadek
Application Number:
JP2019535971A
Publication Date:
November 14, 2019
Filing Date:
September 12, 2017
Export Citation:
Assignee:
Haprogen Gamebha
International Classes:
C07C237/06; A61K31/165; A61K31/166; A61K31/167; A61K31/18; A61K31/341; A61K31/351; A61K31/397; A61K31/4015; A61K31/4025; A61K31/403; A61K31/4035; A61K31/4155; A61K31/417; A61K31/4196; A61K31/42; A61K31/422; A61K31/4245; A61K31/427; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4412; A61K31/4439; A61K31/445; A61K31/4453; A61K31/45; A61K31/454; A61K31/472; A61K31/495; A61K31/4965; A61K31/497; A61K31/506; A61K31/55; A61P3/04; A61P31/00; A61P31/14; A61P35/00; C07C235/74; C07C237/04; C07C237/08; C07C237/12; C07C237/14; C07C237/20; C07C311/06; C07C311/13; C07C311/19; C07C311/29; C07D205/04; C07D207/27; C07D211/26; C07D211/76; C07D213/40; C07D213/76; C07D213/81; C07D213/82; C07D217/06; C07D233/64; C07D241/12; C07D261/18; C07D295/15; C07D307/14; C07D309/04; C07D309/06; C07D309/14; C07D401/12; C07D403/06; C07D403/12; C07D405/06; C07D405/12; C07D409/06; C07D413/12; C07D417/06; C07D417/12
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JOURNAL OF ORGANIC CHEMISTRY, vol. 73, no. 22, JPN6021026182, 2008, pages 8780 - 8784, ISSN: 0004848670
日本化學雜誌, vol. 89, no. 7, JPN6021026181, 1968, pages 714 - 716, ISSN: 0004848671
CHICHENG MA; ET AL: "PHOTOCHEMICAL CLEAVAGE AND RELEASE OF PARA-SUBSTITUTED PHENOLS FROM α-KETO AMIDES", JOURNAL OF ORGANIC CHEMISTRY, vol. VOL:71, NR:11, JPN5019008259, May 2006 (2006-05-01), US, pages 4206 - 4215, ISSN: 0004848666
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 23, JPN6021026180, 2010, pages 6890 - 6894, ISSN: 0004848672
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, no. 4, JPN6021026176, 2002, pages 641 - 643, ISSN: 0004848673
OTA EISUKE; ET AL: "PHOTO-INDUCED FORMATION OF CYCLOPROPANOLS FROM α-KETOAMIDES VIA γ-C-H BOND ACTIVATION", TETRAHEDRON LETTERS, vol. VOL:56, NR:44, JPN5019008260, 15 September 2015 (2015-09-15), pages 5991 - 5994, ISSN: 0004848667
OCAIN T D; RICH D H: "α-KETO AMIDE INHIBITORS OF AMINOPEPTIDASES", JOURNAL OF MEDICINAL CHEMISTRY, vol. VOL:35, NR:3, JPN5019008261, January 1992 (1992-01-01), US, pages 451 - 456, ISSN: 0004848668
HANS-JOACHIM KABHE: "UMSETZUNGEN VON 2.3-BIS-ALKYLIMINO-OXETANEN", CHEM. BER., vol. 102, JPN5019008262, January 1969 (1969-01-01), pages 1410 - 1417, XP055426620, ISSN: 0004848669
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Hirose Shinobu
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Hirose Shinobu