To obtain an apparatus in which serum or plasma is separated quickly from whole blood while the serum or the plasma in a minimum amount is being held in the gap of a matrix by a method wherein the matrix has a pore diameter selected in such a way that individual red corpuscles are passed and that aggregated red corpuscles are held.
An apparatus is composed of a matrix for a hydrophilic sintered porous substance in which at least one kind of a red corpuscle flocculant is built. The matrix has a pore diameter selected in such a way that individual red corpuscles are passed through the matrix and that aggregated cells are held by the matrix. The apparatus quickly separates serum or plasma from whole blood while only the serum or the plasma in a minimum residual amount is being held inside the gap of the porus substance. The pore diameter of the matrix is selected in such a way that substantially all red corpuscles existing in the whole blood are aggregated so as to be held in the matrix by taking into consideration the length and the volume of the matrix, the volume of a blood sample to be treated and a cabability by which the flocculant aggregates the red corpuscles.
ELMORE KRISTIN D
GEORGEVICH GRADIMIR G
JENG TZYY-WEN
OOSTA GARY M
TERRY A PREY
SIEGEL NEAL A
KATHY R SILVERMAN
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