To provide a two-dimensional imaging apparatus by which can increase resolution in mass spectrometry and a signal-to-noise ratio to acquire an accurate two-dimensional image, even when biological tissue and chemicals, which include molecules with weak chemical bonds therein are set as measurement objects.
A two-dimensional imaging apparatus is provided with a laser source 11; a sample stand 13 whereon samples 90 including measurement objects are placed; an optical system 30 which guides an infrared laser beam from the laser source 11 to the sample 90; a movement mechanism which relatively displaces the optical system 30 and the sample stand 13; a mass spectrometry unit 14 which separates ions, which the sample 90 generates by receiving an infrared laser beam, on the basis of the mass electric charge ratio of the ions; and an ion detector 17 which detects ions. A mass spectrum is acquired per part of a plurality of parts in the sample 90 where a matrix is applied and is stored after being associated with coordinate positions for each of the parts. A concentration map is created in accordance with the peak intensity indicating mass of specific molecules included in the measurement object.
MORIMOTO IWAO
YOKOYAMA MINORU
YANASE ETSUYA
WADA YOSHINAO
TAJIRI MICHIKO
JP2007309860A | 2007-11-29 | |||
JP2005517954A | 2005-06-16 |
WO2008129850A1 | 2008-10-30 | |||
US20100044563A1 | 2010-02-25 |
Mitsuo Tanaka
Yukinori Nakakura
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