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Title:
核酸送達試薬の調製における化合物または伝統的漢方薬抽出物の応用およびその関連生成物
Document Type and Number:
Japanese Patent JP7252132
Kind Code:
B2
Abstract:
The present application relates to extracting, from a traditional Chinese medicine, a plurality of compounds capable of prompting nucleic acid delivery or synthetic compounds, and promoting nucleic acid such as sRNA to absorb and enter a target cell using the extracted compounds or a plurality of combinations and promoting the nucleic acid to enter required target sites in vivo of an object.

Inventors:
Jean, Cheng Woo
Doo, Jang Chao
Liang
Li, Xiao Yun
Application Number:
JP2019553884A
Publication Date:
April 04, 2023
Filing Date:
March 29, 2018
Export Citation:
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Assignee:
Institute of Basic Medical Sciences Chinese Academy of Medical Sciences
International Classes:
A61K9/127; A61K31/7088; A61K31/7105; A61K31/711; A61K31/713; A61K47/14; A61K47/18; A61K47/24; A61K48/00; A61P1/04; A61P11/00; A61P35/00; C07C31/22; C07C57/12; C07C69/30; C07C215/10; C07C233/18; C07F9/09
Domestic Patent References:
JP2006524707A
Foreign References:
US6074667
WO2009059201A2
WO2016004318A1
WO2015187966A1
Other References:
Nucleic Acids Research,2002年,Vol.30, No.8,pp.1808-1816
Attorney, Agent or Firm:
Shinsuke Umeda
Yuko Matsutoya
Yu Morita
Chisuke Konno
Nobuto Oki