To provide an efficient method for preparing a stable aqueous dispersion of microparticles comprising nanoparticulates.
The stable aqueous dispersion of microparticles comprising nanoparticulates is prepared by: (a) providing a plurality of nanoparticulates having an average particle size of 300 nm or less; (b) admixing the nanoparticulates with (1) one or more polymerizable ethylenically unsaturated monomers and/or (2) a mixture of one or more polymerizable unsaturated monomers with one or more polymers and/or (3) one or more polymers, to form an admixture; (c) subjecting the admixture to high stress shear conditions in the presence of an aqueous medium to particularize the admixture into microparticles; and (d) optionally, polymerizing the ethylenically unsaturated monomers under free radical polymerization conditions.
KULFAN ANTHONY D
O'DWYER JAMES B
DECKER ELDON L
WOODWORTH BRIAN E
RARDON LORI S
Takaaki Yasumura
Natsuki Morishita
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