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Title:
The Aryl (hetero) cyclo propylamine compound as LSD1 inhibitor
Document Type and Number:
Japanese Patent JP6215212
Kind Code:
B2
Abstract:
The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula I as described and defined herein, and their use in therapy, including,e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.

Inventors:
Albert Ortega Munoz
Mateu Colin Thor Fife
Marc Martinel Pedmont
Maria de los angeles estialte martinez
Nuria Bals Vidal
Guido Cruz
Julio Cesar Castro Palomino Laria
Application Number:
JP2014536286A
Publication Date:
October 18, 2017
Filing Date:
October 22, 2012
Export Citation:
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Assignee:
ORYZON GENOMICS S.A.
International Classes:
C07D205/04; A61K31/351; A61K31/382; A61K31/397; A61K31/40; A61K31/403; A61K31/438; A61K31/439; A61K31/4433; A61K31/445; A61K31/4462; A61K31/4465; A61K31/4468; A61K31/454; A61K31/4545; A61K31/4706; A61K31/55; A61P1/16; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/24; A61P25/28; A61P31/12; A61P31/14; A61P31/18; A61P31/20; A61P31/22; A61P35/00; A61P35/02; C07D207/09; C07D207/14; C07D209/54; C07D211/26; C07D211/56; C07D211/58; C07D215/42; C07D221/20; C07D223/12; C07D309/04; C07D309/14; C07D335/02; C07D401/04; C07D401/12; C07D405/12; C07D417/12; C07D451/04
Domestic Patent References:
JP57188590A
JP2007505088A
JP2004126566A
Foreign References:
WO2013022047A1
WO2007035873A1
WO2010084160A1
Other References:
Aboul-Enein, M. Nabil et al.,Synthesis of some 4-substituted amino-1-methylpiperidines structurally related to antihistaminics,Pharmaceutica Acta Helvetiae ,1973年,48(3),151-6
Attorney, Agent or Firm:
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto