Title:
抗炎症剤及び鎮痛剤としてのアリール又はヘテロアリール縮合イミダゾール化合物
Document Type and Number:
Japanese Patent JP4060182
Kind Code:
B2
Abstract:
This invention provides a compound of the following formula:
or salts thereof,
and a compound of the following formula:
or salts thereof,
wherein Y 1 , Y 2 , Y 3 and Y 4 are independently selected from N, CH, etc.; R 1 is H, C 1-8 alkyl, etc.; A is an optionally substituted benzene or pyridine ring; B is C 2-6 alkylene etc.; W is NH or O; and P is H, protecting group etc.. These compounds are useful as intermediates for the preparation of compounds for the treatment of medical conditions mediated by prostaglamndin such as pain, fever or inflammation, etc.
Inventors:
Kazushige Nakao
Okumura Shosei
Matsumizu capital
Naomi Ueno
Yoshinobu Hashizume
Tomoki Kato
Akiyoshi Kawai
Kyoko Miyake
Seiji Nakai
Katsuhiro Shinjo
Kana Taniguchi
Okumura Shosei
Matsumizu capital
Naomi Ueno
Yoshinobu Hashizume
Tomoki Kato
Akiyoshi Kawai
Kyoko Miyake
Seiji Nakai
Katsuhiro Shinjo
Kana Taniguchi
Application Number:
JP2002536282A
Publication Date:
March 12, 2008
Filing Date:
October 15, 2001
Export Citation:
Assignee:
Pfizer Japan Inc
International Classes:
C07D235/06; G01N33/48; A61K31/00; A61K31/4178; A61K31/4184; A61K31/4188; A61K31/427; A61K31/437; A61K31/4439; A61K31/444; A61K31/454; A61K31/4725; A61K31/506; A61K31/52; A61K31/64; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P3/10; A61P5/00; A61P7/02; A61P7/04; A61P7/08; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P11/02; A61P11/06; A61P13/12; A61P15/04; A61P15/06; A61P17/00; A61P17/02; A61P17/16; A61P19/02; A61P19/06; A61P19/08; A61P19/10; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/20; A61P25/28; A61P27/00; A61P27/06; A61P29/00; A61P31/12; A61P31/16; A61P31/18; A61P35/00; A61P35/04; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D235/08; C07D235/12; C07D235/14; C07D235/16; C07D235/30; C07D401/04; C07D401/06; C07D401/12; C07D403/04; C07D403/06; C07D403/12; C07D413/12; C07D417/04; C07D417/12; C07D471/04; C07D473/00; C07D491/04; C07D491/048; C07D491/056; C07D521/00; G01N33/15; G01N33/50; C07D235/10
Domestic Patent References:
| JP5505199A | ||||
| JP1254678A | ||||
| JP5507064A | ||||
| JP2000191615A |
Other References:
Bioorganic and Medicinal Chemistry Letters,1994年,4(1),133-8
Attorney, Agent or Firm:
Yoshinobu Murofushi