Title:
アリール置換およびヘテロアリール置換テトラヒドロベンゾ-1,4-ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
Document Type and Number:
Japanese Patent JP2010526825
Kind Code:
A
Abstract:
The aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepine derivative compounds of the present invention are represented by formulae 1(A-D) having the following structure: where the substituents X and R1-R8 are as defined herein.
Inventors:
Guzzo Peter Earl.
Molino Bruce F.
Kui Wen
Ryu Showan
Olson Richard E.
Molino Bruce F.
Kui Wen
Ryu Showan
Olson Richard E.
Application Number:
JP2010507653A
Publication Date:
August 05, 2010
Filing Date:
May 08, 2008
Export Citation:
Assignee:
AMR Technology Inc.
BRISTOL-MYERS SQUIBB COMPANY
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D243/14; A61K31/198; A61K31/5513; A61K45/00; A61P1/14; A61P3/00; A61P3/04; A61P13/02; A61P15/00; A61P15/10; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/14; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P25/36; A61P43/00; C07D401/04; C07D403/04; C07D405/14; C07D471/04
Foreign References:
| WO2007011820A2 | 2007-01-25 |
Other References:
JPN6013027683; Ａｒｃｈｉｖ ｄｅｒ Ｐｈａｒｍａｚｉｅ Ｖｏｌ．３１７， Ｎｏ．７, 1984, ｐ．５９５-６０６
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto