Title:
ARYLCARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND ITS APPLICATION
Document Type and Number:
Japanese Patent JP2009155250
Kind Code:
A
Abstract:
To provide a new low-molecular weight compound that exhibits enhanced actions on an intranuclear receptor RAR and has antitumor activity based on an RAR transcription activating action.
The arylcarboxylic acid compound is represented by general formula (I) [wherein X is an oxygen atom or a sulfur atom; Ar is an aryl group or a heteroaryl group; R1 and R2 are the same or different and are each a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group; and R3 is a hydrogen atom or a lower alkyl group]. A pharmacologically acceptable salt thereof is also provided.
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Inventors:
ENKAI HIROMI
MURAKAMI KOJI
MURAKAMI KOJI
Application Number:
JP2007334147A
Publication Date:
July 16, 2009
Filing Date:
December 26, 2007
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD
International Classes:
C07F7/10; A61K31/695; A61P17/06; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07F7/12
Attorney, Agent or Firm:
Eiji Saegusa
Mutsuko Nakano
Masahito Hayashi
Mutsuko Nakano
Masahito Hayashi