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Title:
アリールメトキシイソインドリン誘導体、それを含む組成物、及びその使用方法
Document Type and Number:
Japanese Patent JP2013519675
Kind Code:
A
Abstract:
Provided are 4'-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed. The compounds are derivatives of hydroxy thalidomide active against cancer.

Inventors:
Hong-Waffman
Georg W. Murrell
Alexander lucermann
Ehab M. Kuharil
Roger Schen-Chucheng
Way Hung Hang
Application Number:
JP2012552978A
Publication Date:
May 30, 2013
Filing Date:
February 10, 2011
Export Citation:
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Assignee:
Celgene Corporation
International Classes:
C07D401/04; A61K31/4365; A61K31/4439; A61K31/444; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/4985; A61K31/506; A61K31/517; A61K31/536; A61K31/5377; A61K31/538; A61K31/5386; A61K31/541; A61K31/553; A61P7/00; A61P9/10; A61P11/00; A61P17/00; A61P21/00; A61P25/00; A61P25/04; A61P25/20; A61P31/00; A61P31/18; A61P33/00; A61P35/00; A61P39/02; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D491/08; C07D491/107; C07D495/04
Domestic Patent References:
JP2002506861A2002-03-05
JP2007505922A2007-03-15
JP2002506861A2002-03-05
JP2007505922A2007-03-15
Foreign References:
WO2008115516A22008-09-25
Other References:
JPN6014049678; Chem. Pharm. Bull. 54(12), 2006, 1709-1714
Attorney, Agent or Firm:
Toru Ishikawa