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Title:
ASSAY METHOD FOR IDENTIFYING AGENT FOR TREATING FEMALE SEXUAL DYSFUNCTION (FSD), METHOD AND KIT FOR DETECTING FEMALE SEXUAL DYSFUNCTION AND NON-HUMAN ANIMAL MODEL OF FEMALE SEXUAL DYSFUNCTION
Document Type and Number:
Japanese Patent JP2005021167
Kind Code:
A
Abstract:

To provide an effective method for treating a female suffering from female sexual dysfunction (FSD), in particular, female sexual arousal dysfunction (FSAD).

A method for assaying an agent capable of potentiating cAMP in the sexual genitalia of the female suffering from female sexual dysfunction, in particular, female sexual arousal dysfunction is provided. The agent is an inhibitor of neuropeptide Y (I:NPY). A method and a kit for detecting female sexual dysfunction, in particular, female sexual arousal dysfunction are provided. Non-human animal models, including an anesthetized female animal having a means for measuring change of genitalial blood flow of the animal accompanied with pelvic nerve stimulation, for identifying the agent for treating female sexual dysfunction, in particular, female sexual arousal dysfunction are provided.


Inventors:
MAW GRAHAM NIGEL (GB)
WAYMAN CHRISTOPHER PETER (GB)
Application Number:
JP2004267669A
Publication Date:
January 27, 2005
Filing Date:
September 15, 2004
Export Citation:
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Assignee:
PFIZER (US)
International Classes:
A01K67/027; A61K31/00; A61K31/122; A61K31/137; A61K31/165; A61K31/17; A61K31/18; A61K31/19; A61K31/191; A61K31/192; A61K31/195; A61K31/196; A61K31/197; A61K31/198; A61K31/215; C12N9/99; A61K31/216; A61K31/223; A61K31/33; A61K31/34; A61K31/341; A61K31/352; A61K31/395; A61K31/40; A61K31/4015; A61K31/403; A61K31/404; A61K31/405; A61K31/41; A61K31/4164; A61K31/4166; A61K31/4184; A61K31/421; A61K31/433; A61K31/437; A61K31/438; A61K31/44; A61K31/4402; A61K31/4412; A61K31/4418; A61K31/4425; A61K31/4427; A61K31/443; A61K31/4439; A61K31/444; A61K31/453; A61K31/454; A61K31/4545; A61K31/47; A61K31/4706; A61K31/495; A61K31/496; A61K31/4985; A61K31/499; A61K31/505; A61K31/506; A61K31/517; A61K31/519; A61K31/52; A61K31/522; A61K31/53; A61K31/548; A61K31/55; A61K31/551; A61K31/553; A61K31/554; A61K31/65; A61K31/661; A61K31/675; A61K38/00; A61K38/12; A61K38/46; A61K38/55; A61K45/00; A61P5/30; A61P9/14; A61P15/00; A61P15/02; A61P15/08; A61P15/12; A61P25/02; A61P43/00; C07C233/58; C07C233/60; C07C311/51; C07D207/26; C07D207/27; C07D209/12; C07D213/64; C07D213/74; C07D213/75; C07D213/80; C07D213/85; C07D215/40; C07D223/10; C07D223/16; C07D233/72; C07D233/78; C07D239/95; C07D251/48; C07D257/06; C07D263/34; C07D267/14; C07D285/135; C07D295/02; C07D295/08; C07D307/14; C07D307/24; C07D307/54; C07D401/04; C07D401/12; C07D403/06; C07D471/14; C07D473/30; C07D473/34; C07D487/04; C07D513/04; C07K14/47; C07K14/705; C12N9/64; C12N9/88; C12N15/09; C12Q1/37; C12Q1/42; C12Q1/44; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/573; G01N33/68; A61K; (IPC1-7): A01K67/027; A61K31/433; A61K45/00; A61P15/00; A61P15/02; A61P25/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami