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Title:
ASSAY OF NUCLEIC ACID SEQUENCE IN NUCLEIC ACID-CONTAINING SPECIMEN
Document Type and Number:
Japanese Patent JPS63313598
Kind Code:
A
Abstract:
A method for detecting (i) one or more microorganisms or (ii) nucleic acid sequences from a prokaryotic source or an eukaryotic source in a nucleic acid-containing test sample comprising (a) labeling the nucleic acids in the test sample, (b) contacting, under hybridization conditions, the labeled hybridizable nucleic acid and one or more immobilized hybridizable nucleic acid probes comprising (i) one or more known microorganisms or (ii) sequences from eukaroytic or prokaryotic sources, to form hybridized labeled nucleic acids, and (d) assaying for the hybridized nucleic acids by detecting the label. The method can be used to detect genetic disorders, e.g., sickle-cell anemia. o

Inventors:
NANIBUFUSHIYAN DATSUTAGUPUTA
PIITAA EMU EMU REI
DANIERU YUU RABIN
EDOWAADO DEI FUGENERU
Application Number:
JP5651788A
Publication Date:
December 21, 1988
Filing Date:
March 11, 1988
Export Citation:
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Assignee:
MOLECULAR DIAGNOSTICS INC
International Classes:
C12Q1/68; C12Q1/6806; G01N33/50; C12Q1/6883; C12Q1/689; (IPC1-7): C12Q1/68; G01N33/50
Domestic Patent References:
JPS6093355A1985-05-25
JPS603497A1985-01-09
JPS61128900A1986-06-16
Attorney, Agent or Firm:
Heiyoshi Odashima