To improve rim assemblage simultaneously with the attainment of compatibility of run-flat traveling performance and riding comfort heretofore impossible only with the improvement of a conventional tire in an assembly of a tire and a wheel.

In this assembly of a pneumatic radial tire 1 and a wheel 7 provided with a disc 12 rigidly fixed to an axle hub, and a rim 8 for supporting the pneumatic radial tire 1, the inner diameters of a pair of bead parts 2, 4 are different from each other, and rim flanges 9, 10 of the rim 8 have different diameters corresponding to the different inner diameters of the bead parts 2, 4. Cushioning members 14 are provided at least partially between the disc 12 and the rim 8.