Title:
不斉触媒およびこれを用いた光学活性アルコール類の製造方法
Document Type and Number:
Japanese Patent JP5727127
Kind Code:
B2
Abstract:
The present invention provides an organic metal compound, a ligand, an asymmetric catalyst, and a process for preparing optically-active alcohols using the asymmetric catalyst. The organic metal compound of the present invention is expressed by the following general formula (1):
wherein in general formula (1), R 1 and R 2 are a mutually identical or mutually different, unsubstituted or substituted alkyl group, aryl group, cycloalkyl group, or R 1 and R 2 are bound to form an alicyclic ring, R 3 is a hydrogen atom or an alkyl group, R 4 is a branched alkyl group or an alkyl group that does or does not form a ring by itself, or an unsubstituted or substituted aryl group, or an unsubstituted or substituted heterocyclic group, Ar is an unsubstituted or substituted cyclopentadienyl group that is bound to M via a À bond, or an unsubstituted or substituted benzene, X is a hydride group or an anionic group, M is ruthenium, rhodium or iridium, L is a solvent molecule or a water molecule, 1 is 1 or 2, m is an integer from 0 to 2, n is 0 or 1, and when n is 0, X does not exist, and * represents asymmetric carbon, wherein R 4 is not a camphor group, a camphor derivative group, an isopropyl group or a phenyl group whenever R 1 and R 2 are both a phenyl group.
Inventors:
Masato Watanabe
Junichi Hori
Junichi Hori
Application Number:
JP2009096520A
Publication Date:
June 03, 2015
Filing Date:
April 10, 2009
Export Citation:
Assignee:
Kanto Chemical Co., Ltd.
International Classes:
C07F15/00; B01J31/28; C07B53/00; C07C29/143; C07C29/145; C07C33/20; C07C33/46; C07C41/26; C07C43/23; C07C201/12; C07C205/19; C07C253/30; C07C255/53; C07C311/03; C07C311/13; C07C311/27; C07F17/02
Domestic Patent References:
| JP2009023941A |
Foreign References:
| WO2007120824A1 | ||||
| WO2005092825A1 | ||||
| WO2008018520A1 |
Other References:
Karno Ng,Synthesis of homochiral pentadentate sulfonamide-based ligands,Tetrahedron: Asymmetry,2001年,V12, N12,P1719-1722
Jerome Hannedouche,A New Class of “Tethered” Ruthenium(II) Catalyst for Asymmetric Transfer Hydrogenation Reactions,Journal of American Chemical Society,2004年,V126, N4,P986-987
Fung Kei (Kathy) Cheung,“Tethered” Ru(II) Catalysts for Asymmetric Transfer Hydrogenation of Ketones,The Journal of Organic Chemistry,2005年,V70, N8,P3188-3197
The use of a [4 + 2] cycloaddition reaction for the preparation of a series of‘tethered’ Ru(II)-diamine and aminoalcohol complexes,Organic & Biomolecular Chemistry,2007年,V5, N7,P1093-1103
Jerome Hannedouche,A New Class of “Tethered” Ruthenium(II) Catalyst for Asymmetric Transfer Hydrogenation Reactions,Journal of American Chemical Society,2004年,V126, N4,P986-987
Fung Kei (Kathy) Cheung,“Tethered” Ru(II) Catalysts for Asymmetric Transfer Hydrogenation of Ketones,The Journal of Organic Chemistry,2005年,V70, N8,P3188-3197
The use of a [4 + 2] cycloaddition reaction for the preparation of a series of‘tethered’ Ru(II)-diamine and aminoalcohol complexes,Organic & Biomolecular Chemistry,2007年,V5, N7,P1093-1103
Attorney, Agent or Firm:
Kiyoji Kuzuwa