Title:
PRODUCTION OF O, O'-DIACYLTARTARIC ACID
Document Type and Number:
Japanese Patent JP3208971
Kind Code:
B2
Abstract:
PURPOSE: To obtain an O, O'-diacyltartaric acid crystal in good operability and high yield without producing a bulk material by hydrolyzing an O, O'- diacyltartaric anhydride in water in the presence of an organic solvent immiscible with water.
CONSTITUTION: An O, O'-diacyltartaric anhydride of formula I (R1 and R2 are each H, a halogen or a 1-3C alkyl) is hydrolyzed in water in the presence of an organic solvent immiscible with water to obtain the objective O, O'- diacyltartaric acid of formula II. As the organic solvent added, especially benzene, toluene, xylene or chlorobenzene is preferably used. The organic solvent is preferably added in an amount of 0.01-0.5 time by weight based on the compound of formula I. The optically active O, O'-diacyltartaric acid is useful as an optically resolving agent for various racemic amines. According to this method, this compound of formula 1 can be produced in a high yield and good operability without causing troubles, e.g. a trouble incapable of taking out O, O'-diacyltartaric acid hydrate from a reactor owing to attaching the hydrate to a wall of the reactor or stirrer, etc., in crystallization.
Inventors:
Toshihiro Fujino
Application Number:
JP31453093A
Publication Date:
September 17, 2001
Filing Date:
November 19, 1993
Export Citation:
Assignee:
Toray Industries, Inc.
International Classes:
C07C51/087; C07C57/38; C07C67/28; C07C69/76; (IPC1-7): C07C67/28; C07C69/76
Other References:
【文献】Chemical Abstracts 97:215901
【文献】Chemical Abstracts 115:207664
【文献】Chemical Abstracts 115:207664
Attorney, Agent or Firm:
Eijiro Tanikawa