Title:
アジスロマイシン含有水性医薬組成物及びその調製方法
Document Type and Number:
Japanese Patent JP3933683
Kind Code:
B2
Abstract:
The invention provides an azithromycin-containing aqueous pharmaceutical composition, which comprises at least one member selected from the group consisting of azithromycin, its anhydride, its hydrate, and pharmaceutically acceptable salts thereof, and at least one member selected from the group consisting of monoethanolamine, diethanolamine, triethanolamine, amino acid, ethylenediaminetetraacetic acid, and pharmaceutically acceptable salts thereof, and which does not comprise boric acid or pharmaceutically acceptable salts thereof; and a method for the preparation of the composition, wherein an azithromycin-containing liquid is maintained at pH of 4.0 or higher throughout the method for the preparation. The composition has good heat and storage stability.
Inventors:
Shuichi Suzuki
Oichi
Yoda Kohei
Oichi
Yoda Kohei
Application Number:
JP2006523771A
Publication Date:
June 20, 2007
Filing Date:
July 04, 2005
Export Citation:
Assignee:
Wakamoto Pharmaceutical Co., Ltd.
International Classes:
A61K31/7052; A61K47/04; A61K47/10; A61K47/12; A61K47/18; A61P31/04; C07H17/00
Domestic Patent References:
| JP2001089378A | ||||
| JP2003040782A | ||||
| JP2002540147A |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama