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Title:
AZOLE COMPOUND
Document Type and Number:
Japanese Patent JP2003321460
Kind Code:
A
Abstract:

To provide an azole compound having the production and secretion- promoting activity of a neurotrophic factor and useful for the prevention and treatment of diabetic neuropathy.

This azole compound is expressed by formula (1) [wherein, R1 is H, a halogen atom, a heterocyclic group which is allowed to be substituted, a thiol group which is allowed to be substituted or an amino group which is allowed to be substituted; A is a cyclic amino group which is allowed to be substituted or -NR2-W-D (wherein, R2 is H or an alkyl; W is a bond or a di-valent acyclic hydrocarbon group: and D is a cyclic group which is allowed to be substituted or an acyl group which is allowed to be substituted); B is a hydrocarbon group which is allowed to be substituted or a heterocyclic group which is allowed to be substituted; X is oxygen, sulfur or nitrogen which is allowed to be substituted; and Y is a bond or a di-valent acyclic hydrocarbon group] or is its salt.


Inventors:
SAKAI NOZOMI
MOMOSE YU
MURASE KATSUTO
HASAMA MASAAKI
Application Number:
JP2003050286A
Publication Date:
November 11, 2003
Filing Date:
February 27, 2003
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D277/20; A61K31/421; A61K31/422; A61K31/426; A61K31/427; A61K31/433; A61K31/4439; A61K31/454; A61K31/496; A61K31/506; A61K31/5377; A61K31/54; A61K31/541; A61K31/551; A61K31/662; A61P3/10; A61P25/00; A61P25/04; A61P43/00; C07D263/32; C07D263/34; C07D263/48; C07D277/30; C07D277/40; C07D413/04; C07D413/12; C07D413/14; C07D417/04; C07D417/14; C07F9/653; C07F9/6539; (IPC1-7): C07D263/34; A61K31/421; A61K31/422; A61K31/426; A61K31/427; A61K31/433; A61K31/4439; A61K31/454; A61K31/496; A61K31/506; A61K31/5377; A61K31/54; A61K31/541; A61K31/551; A61K31/662; A61P3/10; A61P25/00; A61P25/04; A61P43/00; C07D263/32; C07D263/48; C07D277/20; C07D277/30; C07D277/40; C07D413/04; C07D413/12; C07D413/14; C07D417/04; C07D417/14; C07F9/653; C07F9/6539
Attorney, Agent or Firm:
Shuichi Takahashi (1 person outside)