Title:
ＢＡＣＥ１阻害剤ペプチド
Document Type and Number:
Japanese Patent JP6814754
Kind Code:
B2
Abstract:
The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
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Inventors:
Beauchamp, Jeremy
Freskugod, Per-Aura
Kitas, Eric Ah
Lyamychev, Victor
Patel, Jigger
Freskugod, Per-Aura
Kitas, Eric Ah
Lyamychev, Victor
Patel, Jigger
Application Number:
JP2017567791A
Publication Date:
January 20, 2021
Filing Date:
July 21, 2016
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
ROCHE NIMBLEGEN,INC.
ROCHE NIMBLEGEN,INC.
International Classes:
C07K7/02; A61K38/08; A61K38/10; A61P3/10; A61P25/28; A61P43/00; C12N9/99
Domestic Patent References:
| JP2015501150A | ||||
| JP2017537098A | ||||
| JP2017537099A |
Other References:
Science Translational Medicine,2011年,Vol.3,No.84,84ra44,p136-143,doi:10.1126/scitranslmed.3002230
Attorney, Agent or Firm:
Patent business corporation Tsukuni