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Patent Searching and Data


Title:
BACTERIAL PHEROMONE AND USE THEREOF
Document Type and Number:
Japanese Patent JP2010011852
Kind Code:
A
Abstract:

To provide a new class of pheromones which stimulate the resuscitation of bacteria after dormancy or resuscitation factor (RP-factor) which may exhibit activity at picomolar concentration since the latent states of pathogenic bacteria become serious medical issues.

RP-factors, their cognate receptors, convertases, respective genes and inhibitors or mimetics thereof are described. In particular, antibodies, pharmaceutical compositions and therapeutic and diagnostic methods based on the RP-factors and their receptors/convertases are described.


Inventors:
Mukamolova, Galina V.
Kaprelyants, Arseny S.
Young, Danielle I.
Kell, Douglas B.
Young, Michael
Application Number:
JP2009000180965
Publication Date:
January 21, 2010
Filing Date:
August 03, 2009
Export Citation:
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Assignee:
ABERYSTWYTH UNIV
International Classes:
C12N15/09; A61K38/00; A61K39/02; A61K39/04; A61K39/395; A61K45/00; A61P31/04; C07K14/195; C07K14/305; C07K14/31; C07K14/315; C07K14/32; C07K14/33; C07K14/335; C07K14/34; C07K14/35; C07K14/36; C07K16/12; C12N1/15; C12N1/19; C12N1/21; C12N1/38; C12N5/10; C12N15/31; C12Q1/68; A61K39/00; C12R1/32; A61K; C07K; C12N; C12Q; G01N
Foreign References:
Other References:
JPN6008025233; Database DDBJ/EMBL/GenBank [online], Accession No.Z81368: <http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?1655639:OLDID:2851296> , 31-OCT-1996 uploaded, Devlin K. et al.
JPN6008025235; Trends Microbiol. Vol.4, No.6, 199606, p.237-242
JPN6008025236; FEMS Microbiol. Lett. Vol.115, No.2-3, 199401, p.347-352
JPN6008025232; Database DDBJ/EMBL/GenBank [online], Accession No.Z94752: <http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?2052120:OLDID:3435248> , 24-APR-1997 uploaded, Murphy L. et al.
JPN6008025234; Database DDBJ/EMBL/GenBank [online], Accession No.D26185: <http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?467326:OLDID:2649853> , 02-SEP-1996 uploaded, Ogasawara N. et al.
Attorney, Agent or Firm:
吉武 賢次
中村 行孝
紺野 昭男
横田 修孝
伊藤 武泰