Title:
BACTERIAL PLAQUE FORMATION INHIBITOR
Document Type and Number:
Japanese Patent JP3112794
Kind Code:
B2
Abstract:
PURPOSE: To obtain the subject inhibitor rich in safety and processability, good in gustatoriness, and containing bacterial plaque formation-suppressive substance(s) extractable efficiently from inexpensive materials.
CONSTITUTION: This bacterial plaque formation inhibitor contains an extract obtained by extraction with a polar solvent (e.g. water, hydrous alcohol) from cacao mass treated with an alkaline agent or from cocoa powder produced by squeezing said cacao mass, or a product obtained by decomposing the extract with an acid, alkali or enzyme. The alkaline agent is e.g. a carbonate, bicarbonate or hydroxide of Na, K, Mg or ammonium, etc. It is preferable that the solubles of said cocoa mass or cocoa powder be extracted by addition of 3-10 weight times of hot water at 70-130°C. The enzyme to be used for decomposing the extract is e.g. a protease, dextranase, hemicellulase. This extract or decomposed product has significantly inhibitory activity against sticking to and build-up on the teeth of glucan due to Streptococcus mutans.
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Inventors:
Yuko Shimizu
Masao Hirayama
Akira Adachi
Masao Hirayama
Akira Adachi
Application Number:
JP3012994A
Publication Date:
November 27, 2000
Filing Date:
February 28, 1994
Export Citation:
Assignee:
Meiji Seika Co., Ltd.
International Classes:
A23G1/30; A23G1/00; A23G3/00; A23G3/34; A23G4/00; A61K8/34; A61K8/66; A61K8/96; A61K8/97; A61K36/00; A61K36/18; A61P1/02; A61Q11/00; (IPC1-7): A61K35/78; A23G1/00; A23G3/00; A23G3/30; A61K7/26; A61P1/02