Title:
塩基性非ペプチド性ブラジキニンアンタゴニスト及びそれから得られた医薬組成物
Document Type and Number:
Japanese Patent JP4293988
Kind Code:
B2
Abstract:
Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified, or the corresponding ammonium quaternary salt. These BK receptor antagonists are a novel class of medicaments which can be used in all the disorders in which the receptors are involved.
Inventors:
Calvani, Federico
Catrambone, Fernando
Ferry Cetti, Patrizia
Finsham, Christopher Ingo
Giolitti, Alessandro
Madge, Carlo Alberto
Quartara, laura
Rossi, Christina
Terraciano, rosa
Catrambone, Fernando
Ferry Cetti, Patrizia
Finsham, Christopher Ingo
Giolitti, Alessandro
Madge, Carlo Alberto
Quartara, laura
Rossi, Christina
Terraciano, rosa
Application Number:
JP2004510790A
Publication Date:
July 08, 2009
Filing Date:
June 05, 2003
Export Citation:
Assignee:
MENARINI RICERCHE S.P.A.
International Classes:
C07D215/26; A61K31/47; A61K31/4709; A61K31/496; A61P1/04; A61P1/16; A61P9/00; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P13/10; A61P13/12; A61P17/00; A61P17/06; A61P17/14; A61P19/02; A61P25/04; A61P29/00; A61P31/04; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D401/12; C07B61/00
Domestic Patent References:
| JP10504840A | ||||
| JP2000502693A | ||||
| JP2000514818A | ||||
| JP2001504854A |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda