Title:
BENZAMIDE DERIVATIVE AS VASOPRESSIN ANTAGONIST AND ITS USE
Document Type and Number:
Japanese Patent JP2008074855
Kind Code:
A
Abstract:
To provide a novel and useful benzamide derivative having vasopressin antagonistic action etc.
This novel benzamide derivative is represented by general formula (I) wherein A is NH etc.; E is -C(=O)- etc.; X is -CH=CH-, -CH=N-, or S; and Y is CH or N, and its salts which are acceptable as a medicine are also included in this invention. Their manufacturing method and medicinal compositions containing them are also included in the invention.
Inventors:
SETOI HIROYUKI
OKAWA TAKEHIKO
YOSHIMITSU TATSUYA
SAWADA HITOSHI
SATO KENTARO
TANAKA HIROKAZU
OKAWA TAKEHIKO
YOSHIMITSU TATSUYA
SAWADA HITOSHI
SATO KENTARO
TANAKA HIROKAZU
Application Number:
JP2007259213A
Publication Date:
April 03, 2008
Filing Date:
September 04, 2007
Export Citation:
Assignee:
ASTELLAS PHARMA INC
International Classes:
C07C237/42; A61K31/165; C07D243/08; A61K31/167; A61K31/17; A61K31/40; A61K31/401; A61K31/41; A61K31/42; A61K31/421; A61K31/426; A61K31/44; A61K31/4427; A61K31/445; A61K31/4468; A61K31/495; A61K31/496; A61K31/505; A61K31/535; A61K31/5375; A61K31/55; A61P1/08; A61P1/16; A61P3/00; A61P3/08; A61P3/10; A61P3/12; A61P7/10; A61P9/00; A61P9/04; A61P9/12; A61P13/02; A61P13/12; A61P15/00; A61P27/16; A61P43/00; C07C231/02; C07C231/12; C07C235/42; C07C237/40; C07C237/44; C07C243/28; C07C255/54; C07C271/16; C07C271/22; C07C271/48; C07C279/08; C07C279/24; C07D207/16; C07D207/34; C07D209/48; C07D211/16; C07D211/44; C07D211/46; C07D211/58; C07D211/74; C07D213/30; C07D213/75; C07D213/80; C07D213/82; C07D239/26; C07D261/04; C07D263/32; C07D277/24; C07D295/16; C07D295/18; C07D295/185; C07D295/192; C07D295/205; C07D295/215; C07D295/26; C07D295/32; C07D401/12
Domestic Patent References:
| JPS6210057A | 1987-01-19 | |||
| JPS60255760A | 1985-12-17 | |||
| JPS608247A | 1985-01-17 | |||
| JPH08333346A | 1996-12-17 | |||
| JPH09190014A | 1997-07-22 | |||
| JPH11500716A | 1999-01-19 | |||
| JP3845869B2 | 2006-11-15 | |||
| JP4042160B |
Foreign References:
| SU1794941A1 | ||||
| SU1754712A1 | 1992-08-15 | |||
| SU1156362A1 | 1991-07-30 | |||
| US4510139A | 1985-04-09 | |||
| US4146386A | 1979-03-27 | |||
| GB865735B | ||||
| US2995488A | 1961-08-08 | |||
| US2802029A | 1957-08-06 |
Attorney, Agent or Firm:
Hamai Kosuke