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Title:
ベンズアミド誘導体
Document Type and Number:
Japanese Patent JP7028780
Kind Code:
B2
Abstract:
The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R 1 , Z and Q are as described in the description.

Inventors:
Shi, Inn
Mi, Lee
Yang, Hanyu
Wan, Shrian
Gong, Den Juan
Bye, Min
Chen, Xiao Chuo
Chen, Yuzier
Chang, Xuejiao
Ma, Yush
Gao, Chinzee
Application Number:
JP2018536326A
Publication Date:
March 02, 2022
Filing Date:
September 30, 2016
Export Citation:
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Assignee:
CIS CHICH CHUCH PHARMACEUTICAL TECHNOLOGY CO., LTD.
International Classes:
C07C233/65; A61K31/40; A61K31/428; A61K31/4418; A61K31/445; A61K31/4535; A61K31/495; A61K31/496; A61K31/50; A61K31/501; A61K31/5375; A61K31/54; A61K31/541; A61K31/55; A61P1/04; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P17/06; A61P19/02; A61P19/06; A61P29/00; A61P35/00; A61P43/00; B01J31/24; C07C231/12; C07C237/28; C07C237/40; C07C237/42; C07C273/00; C07C275/42; C07D211/16; C07D211/46; C07D213/81; C07D213/82; C07D237/24; C07D277/82; C07D295/192; C07D333/38; C07D401/06; C07D401/12; C07D403/12; C07D409/06
Domestic Patent References:
JP2006523193A
JP2006523194A
JP2005511532A
JP2005519932A
JP2005538100A
JP2007501831A
JP2007500129A
JP2007519694A
JP2008515898A
Foreign References:
WO2008152099A2
Other References:
Aston, Nicola M. et al.,p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of aSeries of Biphenylamides to Give a Molecule Suitable for Clinical Progression,Journal of Medicinal Chemistry ,2009年,Vol.52(20),p.6257-6269
Norman, Peter,Investigational p38 inhibitors for the treatment of chronic obstructive pulmonary disease,Expert Opinion on Investigational Drugs ,2015年,Vol.24(3),p.383-392
Attorney, Agent or Firm:
Shigeki Yamakawa
Yuzo Koike