Title:
BENZANILIDE
Document Type and Number:
Japanese Patent JPH03178954
Kind Code:
A
Abstract:
NEW MATERIAL: A benzanilide derivative of formula I [R1 is a C4-18 alkyl; R2 is H, methyl or ethyl; R3 is a halogen, C1-5 alkyl, -OY (Y is an alkyl), -SOnY or dimethylamino; R4 and R5 are each H, an alkyl, -(CH2)m-Z- [Z is -OCH3, -SOqCH3 or -N(CH3)2; m is 2-4]; X is O, -OCH2-, -SOp-, etc.; n, p and q are each 0-2].
EXAMPLE: N-[2-methylthio-5-(2-methoxyethylaminocarbonyl)]phenyl-4- decyloxybenzamide.
USE: Anti-atherosclerotic agents.
PROCESS: An aniline of formula II is reacted with a compound of formula III (Z1 is a halogen or alkoxycarbonyloxy) or an anhydride of formula IV to give the compound of formula I.
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Inventors:
ANDORUU UIRIAMU BURITSUJI
Application Number:
JP25205390A
Publication Date:
August 02, 1991
Filing Date:
September 25, 1990
Export Citation:
Assignee:
RHONE POULENC SANTE
International Classes:
A61K31/165; A61K31/255; A61P9/10; C07C231/02; C07C235/56; C07C237/42; C07C317/28; C07C317/50; C07C323/41; C07C323/42; C07C233/65; C07C323/62; C07C323/63; C07D207/09; C07D213/40; C07D275/03; C07D285/135; C07D295/192; C07D307/52; C07D275/02; C07D285/12; (IPC1-7): A61K31/165; A61K31/255; C07C231/02; C07C235/56; C07C237/42; C07C317/28; C07C317/50; C07C323/42; C07C323/63; C07D213/40
Attorney, Agent or Firm:
Heiyoshi Odashima
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