Title:
未分化リンパ腫キナーゼを阻害するベンゾイミダゾール化合物およびアザベンゾイミダゾール化合物
Document Type and Number:
Japanese Patent JP5795635
Kind Code:
B2
Abstract:
Compounds of Formula (I) are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.
Inventors:
Boesio, Christiane M.
Chen, Alan Si.
Showket, deborah
Ruwis, Richard Tea.
Potashman, Michelle H.
Romero, Carina
Sterwagen, John Sea.
Whittington, Douglas A.
Chen, Alan Si.
Showket, deborah
Ruwis, Richard Tea.
Potashman, Michelle H.
Romero, Carina
Sterwagen, John Sea.
Whittington, Douglas A.
Application Number:
JP2013523206A
Publication Date:
October 14, 2015
Filing Date:
July 28, 2011
Export Citation:
Assignee:
Amgen Incorporated
International Classes:
C07D235/30; A61K31/4184; A61K31/4196; A61K31/437; A61K31/4439; A61K31/444; A61K31/454; A61K31/4545; A61K31/496; A61K31/4985; A61K31/4995; A61K31/501; A61K31/5377; A61K31/541; A61P35/00; A61P43/00; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/08; C07D417/12; C07D471/04; C07D487/04; C07D487/08
Domestic Patent References:
| JP2006528638A | ||||
| JP2005532251A | ||||
| JP2013526569A | ||||
| JP7133224A |
Foreign References:
| WO2010067067A1 | ||||
| US20080200371 | ||||
| WO2011099832A1 | ||||
| WO2010126922A1 | ||||
| WO2009013126A1 |
Other References:
Bioorganic Chemistry,2007年,35(4),344-353
Bioorganic and Medicinal Chemistry Letters,2006年,16,2842-2845
Bioorganic and Medicinal Chemistry Letters,2006年,16,2842-2845
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita