Title:
BENZIMIDAZOLE DERIVATIVE
Document Type and Number:
Japanese Patent JP2005289816
Kind Code:
A
Abstract:
To provide a benzimidazole derivative which acts as a nociceptin receptor antagonist and is useful for medicaments.
The medicament contains as an active ingredient a benzimidazole typified by a compound represented by formula [I] (wherein X is a halogen or a hydrogen atom; B is a halogen, a cyano group, or an optionally fluorine-substituted lower alkyl group; D is a three- to ten-membered alicyclic-heterocyclic ring or the like; R3, R4, and R5, which are the same as or different from each other, are each a hydrogen atom, an optionally substituted lower alkyl group, or the like; and a is 0 or 1).
Inventors:
KOBAYASHI KENSUKE
TAKAHASHI HIROBUMI
KAWAMOTO HIROSHI
KATO TETSUYA
ITO SATOSHI
YOSHIZUMI TAKASHI
OKAMOTO OSAMU
TAKAHASHI HIROBUMI
KAWAMOTO HIROSHI
KATO TETSUYA
ITO SATOSHI
YOSHIZUMI TAKASHI
OKAMOTO OSAMU
Application Number:
JP2002254039A
Publication Date:
October 20, 2005
Filing Date:
August 30, 2002
Export Citation:
Assignee:
BANYU PHARMA CO LTD
International Classes:
A61K31/496; A61P3/04; A61P7/12; A61P9/00; A61P9/02; A61P13/02; A61P25/00; A61P25/04; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P25/36; A61P43/00; C07D235/12; C07D235/14; C07D401/14; C07D235/24; C07D401/04; C07D401/06; C07D403/04; C07D403/08; C07D403/14; C07D405/06; C07D405/14; C07F7/10; C07D235/10; (IPC1-7): C07D401/14; A61K31/496; A61P3/04; A61P7/12; A61P9/02; A61P25/00; A61P25/04; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P25/36; A61P43/00; C07D403/04; C07D403/14; C07D405/14; C07F7/10