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Title:
ベンズイミダゾール−プロリン誘導体
Document Type and Number:
Japanese Patent JP5814491
Kind Code:
B2
Abstract:
The present invention relates to compounds of the formula (II)wherein Ar1, R1, R2, R3, R4a, R4b and (R5)n are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (II), and especially to their use as orexin receptor antagonists.

Inventors:
Christoph Boss
Christine blotch
Marcus Gude
Bivia Hydeman
Thierry Schifferlen
Jody Tea Williams
Application Number:
JP2015515624A
Publication Date:
November 17, 2015
Filing Date:
June 03, 2013
Export Citation:
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Assignee:
Actelion Pharmaceuticals Ltd
International Classes:
C07D401/14; A61K31/4184; A61K31/4188; A61K31/4192; A61K31/4245; A61K31/427; A61K31/4439; A61K31/497; A61K31/506; A61P25/00; A61P25/18; A61P25/20; A61P25/22; A61P25/28; A61P43/00; C07D403/04; C07D403/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D491/056
Domestic Patent References:
JP2005501027A
Attorney, Agent or Firm:
Mitsue Obuchi
Yukio Fuse