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Patent Searching and Data


Title:
BENZOCARBACYCLINE DERIVATIVE AND PRODUCTION THEREOF
Document Type and Number:
Japanese Patent JPH0776550
Kind Code:
A
Abstract:

PURPOSE: To provide the novel compound having platelet coagulation-inhibitory activity, also good in chemical stability.

CONSTITUTION: The compound of formula I (R is 4-7C saturated or unsaturated alkyl, or the above-mentioned alkyl having 1-3C alkyl as branched chain, cyclopentyl or cyclohexyl; X and Y are such that one of them is CH2, the other being O, or X-Y is CH=CH) or a medicinally usable salt thereof, e.g. 4{(2RS,3 RS,3aSR,8aS)-2-hydroxy-3-[(3SR and RS)-3-hydroxyoct-1-enyl]-1,2,3,3a,8,8d- hexahydrocyclopenta[a]-inden-7-yl}butyric acid. The compound of the formula I can be obtained by hydrolyzing a compound of formula II or III.


Inventors:
TOMIYAMA TAKESHI
IKEGAMI SHIRO
HASHIMOTO SHUNICHI
IMAMAKI TAKEYUKI
Application Number:
JP22149193A
Publication Date:
March 20, 1995
Filing Date:
September 06, 1993
Export Citation:
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Assignee:
KOTOBUKI SEIYAKU CO LTD
International Classes:
A61K31/19; A61P7/02; C07C59/54; (IPC1-7): C07C59/54; A61K31/19
Attorney, Agent or Firm:
Hiroshi Tanaka (1 outside)