BENZOOXAZEPINE COMPOUND

Japanese Patent JP2007332154

A

To provide a compound more useful for a medicine, useful for prevention and medication of hyperlipidemia through activities of lowering cholesterol-level and lowering triglyceride-level by inhibitory activities to enzymes for synthesizing squalene, that is, a benzoxazepine compound useful for prevention and medication of hyperlipidemia having activities of lowering cholesterol-level and lowering triglyceride-level.

A lipid-lowering medicine or composition comprises a compound or a salt thereof represented by formula (I), wherein R is a lower alkyl group optionally substituted with a hydroxyl group; X is an optionally substituted carbamoyl group or an optionally substituted heterocyclic group having a deprotonatable hydrogen atom; R1is a lower alkyl group; and W is a halogen atom.

COPYRIGHT: (C)2008,JPO&INPIT

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YUKIMASA HIDEFUMI
SUGIYAMA YASUO
TOZAWA RYUICHI

JP2007210503A

December 27, 2007

August 10, 2007

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TAKEDA CHEMICAL INDUSTRIES LTD

C07D267/14; A61K31/553; A61K31/675; A61P3/06; A61P43/00; C07D413/04; C07D413/12; C07D413/14; C07D491/113; C07F9/6527

Takashima Ichi

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