Title:
Benzoxazinone amide as a mineralocorticoid receptor modifier
Document Type and Number:
Japanese Patent JP6368383
Kind Code:
B2
Abstract:
Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, that act as mineralocorticoid (MR) receptor modulators that may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
Inventors:
Gavin Omahoney
Mikel Kossenyans
Karl Edman
Johann Kajanus
Karl Andesh Hogner
Philip Cornwall
Andrew Turner
Mikel Kossenyans
Karl Edman
Johann Kajanus
Karl Andesh Hogner
Philip Cornwall
Andrew Turner
Application Number:
JP2016575499A
Publication Date:
August 01, 2018
Filing Date:
June 26, 2015
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
C07D265/36; A61K31/538; A61P9/00; A61P9/04; A61P9/12; A61P13/12
Domestic Patent References:
| JP2008508314A | ||||
| JP2009051830A | ||||
| JP2008506689A | ||||
| JP2006512357A |
Other References:
Bioorg. Med. Chem,2013年,21,5983-5994
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai